Treat Multiple Symptoms of Migraine1-3

What symptoms does CAMBIA treat?

CAMBIA was studied in 2 clinical trials comparing a single dose of CAMBIA to placebo for the treatment of migraine headache.1 CAMBIA was shown to treat the pain and common symptoms associated with acute migraine attacks in adults, including nausea, sensitivity to light (photophobia), and sensitivity to sound (phonophobia).1,2


A study of CAMBIA (n=343) vs placebo (n=347) for the treatment of acute migraine in 690 patients.

IMPORTANT SAFETY INFORMATION

CAMBIA should only be used:

  • exactly as prescribed
  • at the lowest dose possible for your treatment
  • for the shortest time needed

Who should not take CAMBIA?

Do not take CAMBIA:

  • if you have had an asthma attack, hives, or other allergic reaction with aspirin, diclofenac, or any other NSAIDs.
  • right before or after heart bypass surgery.

Migraine Pain Relief

Does CAMBIA relieve migraine pain?

In a clinical study of 328 patients, 24.7% of those taking a single dose of CAMBIA were pain-free at 2 hours compared to 11.7% taking placebo.3

How quickly did CAMBIA start working?

A secondary component to the above trial was designed to look at how quickly a single dose of 50 mg CAMBIA worked compared to diclofenac potassium tablets. CAMBIA was shown to work in as fast as 15 minutes in some patients versus 60 minutes for diclofenac potassium tablets.3

IMPORTANT SAFETY INFORMATION

Before taking CAMBIA, tell your healthcare provider about all your medical conditions, including if you:

  • have liver or kidney problems
  • have a history of stomach ulcer or bleeding in your stomach or intestines
  • have any allergies to any medicines
  • have chest pain, shortness of breath, irregular heartbeats
  • have high blood pressure
  • have asthma
  • are pregnant, think you might be pregnant, or are trying to become pregnant. CAMBIA should not be used by pregnant women, especially after 29 weeks of pregnancy unless directed by your healthcare provider to do so. CAMBIA may cause problems in your unborn child or complications during your delivery
  • are breastfeeding or plan to breastfeed. It is not known if CAMBIA passes into your breast milk. You and your doctor should decide if you will take CAMBIA or breastfeed. You should not do both
  • have a headache that is different from your usual migraine

References

1. CAMBIA [package insert]. Newark, CA: Depomed, Inc; 2016. 2. Lipton RB, Grosberg B, Singer RP, et al. Efficacy and tolerability of a new powdered formulation of diclofenac potassium for oral solution for the acute treatment of migraine: results from the International Migraine Pain Assessment Clinical Trial (IMPACT). Cephalalgia. 2010;30(11):1336-1345. 3. Diener HC, Montagna P, Gács G, et al. Efficacy and tolerability of diclofenac potassium sachets in migraine: a randomized, double-blind, cross-over study in comparison with diclofenac potassium tablets and placebo. Cephalalgia. 2006;26(5):537-547.